DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked
Tissue Specificity
A synthetic peptide corresponding to residues near the C-terminus of human HSF2 was used as an immunogen
Cellular Localization
Cytoplasm. Nucleus. Note=Cytoplasmic during normal growth and moves to the nucleus upon activation