Application
Figure 1: Western blot analysis using anti-IL16 monoclonal antiobdy against IL16 recombinant protein.| Product Name | IL-16 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IL16 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 5D8 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500 - 2000. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | IL16 |
|---|---|
| Molecular Weight(MW) | 141752 Da |
| Function | Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 Isoform 3 is involved in cell cycle progression in T- cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells |
| Tissue Specificity | Isoform 3 is expressed in hemopoietic tissues, such as resting T-cells, but is undetectable during active T-cell proliferation |
| Cellular Localization | Interleukin-16: Secreted. Isoform 3: Cytoplasm. Nucleus. |
| Entrez Gene | 3603 |
|---|---|
| Nucleotide Accession | NP_757366.2 |
Application
Figure 1: Western blot analysis using anti-IL16 monoclonal antiobdy against IL16 recombinant protein.| Application Notes | WB:1:500 - 2000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of human IL-16 expressed in E. Coli. |
