Application
A. Western blot analysis on Jurkat cell lysate using anti-IL-1R1 RabMAb (Cat. #AJ1396a), dilution 1:2,000.| Product Name | IL-1R1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IL1R1, IL1R, IL1RA, IL1RT1, Interleukin-1 receptor type I, IL-1R-1;IL-1RT1;IL-1R-alpha;p80;CD121 antigen-like family member A |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP409Y |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IL1R IL1RA IL1RT1 |
|---|---|
| Alternative Names | IL1R1 IL1R IL1RA IL1RT1 Interleukin-1 receptor type I IL-1R-1 IL-1RT1 IL-1R-alpha p80 CD121 antigen-like family member A |
| Molecular Weight(MW) | 65402 Da |
| Function | Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex |
| Tissue Specificity | A synthetic peptide corresponding to residues near the N-terminus of human IL-1R type 1 was used as immunogen. |
| Cellular Localization | Membrane; Single-pass type I membrane protein. Cell membrane (Probable). Secreted |
| Entrez Gene | 3554 |
|---|
Application
A. Western blot analysis on Jurkat cell lysate using anti-IL-1R1 RabMAb (Cat. #AJ1396a), dilution 1:2,000.| Application Notes | WB:1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
