Application
IL1R1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the IL1R1 antibody detected the IL1R1 protein (arrow).Application
IL1R1 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the IL1R1 antibody detected the IL1R1 protein (arrow).| Product Name | IL1R1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IL1R1; IL1R; IL1RA; IL1RT1; Interleukin-1 receptor type 1; CD121 antigen-like family member A; Interleukin-1 receptor alpha; Interleukin-1 receptor type I; p80; CD_antigen=CD121a; Interleukin-1 receptor type 1, membrane form; Interleukin-1 receptor type 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IL1R IL1RA IL1RT1 |
|---|---|
| Alternative Names | IL1R1 IL1R IL1RA IL1RT1 Interleukin-1 receptor type 1 CD121 antigen-like family member A Interleukin-1 receptor alpha Interleukin-1 receptor type I p80 CD_antigen=CD121a Interleukin-1 receptor type 1 membrane form Interleukin-1 receptor type 1 |
| Molecular Weight(MW) | 65402 Da |
| Function | Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex |
| Tissue Specificity | This IL1R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 421-450 amino acids from the C-terminal region of human IL1R1. |
| Cellular Localization | Membrane; Single-pass type I membrane protein. Cell membrane (Probable). Secreted |
| Entrez Gene | 3554 |
|---|---|
| Nucleotide Accession | NP_000868.1 |
Application
IL1R1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the IL1R1 antibody detected the IL1R1 protein (arrow).
Application
IL1R1 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the IL1R1 antibody detected the IL1R1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
