Application
IL1R2 Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the IL1R2 antibody detected the IL1R2 protein (arrow).| Product Name | IL1R2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IL1R2; IL1RB; Interleukin-1 receptor type 2; CD121 antigen-like family member B; CDw121b; IL-1 type II receptor; Interleukin-1 receptor beta; Interleukin-1 receptor type II; CD_antigen=CD121b; Interleukin-1 receptor type 2, membrane form; Interleukin-1 re |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IL1RB |
|---|---|
| Alternative Names | IL1R2 IL1RB Interleukin-1 receptor type 2 CD121 antigen-like family member B CDw121b IL-1 type II receptor Interleukin-1 receptor beta Interleukin-1 receptor type II CD_antigen=CD121b Interleukin-1 receptor type 2 membrane form Interleukin-1 re |
| Molecular Weight(MW) | 45421 Da |
| Function | Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors |
| Tissue Specificity | This IL1R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-300 amino acids from the Central region of human IL1R2. |
| Cellular Localization | Isoform Short: Secreted. |
| Entrez Gene | 7850 |
|---|---|
| Nucleotide Accession | NP_004624.1 NP_775465.1 |
Application
IL1R2 Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the IL1R2 antibody detected the IL1R2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
