ITA6 Antibody(Ascites)(Cat. #AM1828b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ITA6 antibody detected the ITA6 protein (arrow).
ITGA6; Integrin alpha-6; CD49 antigen-like family member F; VLA-6; CD_antigen=CD49f; Integrin alpha-6 heavy chain; Integrin alpha-6 light chain
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
129CT49.6.5
Host Species
Mouse
Tested Applications
WB
WB:1:200~1600
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Alternative Names
ITGA6 Integrin alpha-6 CD49 antigen-like family member F VLA-6 CD_antigen=CD49f Integrin alpha-6 heavy chain Integrin alpha-6 light chain
Molecular Weight(MW)
126633 Da
Function
Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome
Tissue Specificity
Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoforms containing segment X1 are ubiquitously expressed. Isoforms containing segment X1X2 are expressed in heart, kidney, placenta, colon, duodenum, myoblasts and myotubes, and in a limited number of cell lines; they are always coexpressed with the ubiquitous isoform containing segment X1. In some tissues (e.g. Salivary gland), isoforms containing cytoplasmic segment A and isoforms containing segment B are detected while in others, only isoforms containing one cytoplasmic segment are found (segment A in epidermis and segment B in kidney)
Cellular Localization
Cell membrane; Single-pass type I membrane protein
ITA6 Antibody(Ascites)(Cat. #AM1828b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ITA6 antibody detected the ITA6 protein (arrow).
Application Notes
WB:1:200~1600
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.