Application
ITGB2 Antibody(Cat. #AM2138b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ITGB2 antibody detected the ITGB2 protein (arrow).| Product Name | ITGB2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ITGB2; CD18; MFI7; Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150, 95 subunit beta; Complement receptor C3 subunit beta; CD_antigen=CD18; Flags: Precursor |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 534CT6.2.1 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CD18 MFI7 |
|---|---|
| Alternative Names | ITGB2 CD18 MFI7 Integrin beta-2 Cell surface adhesion glycoproteins LFA-1/CR3/p150 95 subunit beta Complement receptor C3 subunit beta CD_antigen=CD18 Flags: Precursor |
| Molecular Weight(MW) | 84782 Da |
| Function | Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha- D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation |
| Tissue Specificity | Purified His-tagged ITGB2 protein(Fragment) was used to produced this monoclonal antibody. |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 3689 |
|---|---|
| Nucleotide Accession | NP_000202.2 |
Application
ITGB2 Antibody(Cat. #AM2138b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ITGB2 antibody detected the ITGB2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
