KIRREL Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the KIRREL antibody detected the KIRREL protein (arrow).
KIRREL; KIRREL1; NEPH1; Kin of IRRE-like protein 1; Kin of irregular chiasm-like protein 1; Nephrin-like protein 1
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
KIRREL1 NEPH1
Alternative Names
KIRREL KIRREL1 NEPH1 Kin of IRRE-like protein 1 Kin of irregular chiasm-like protein 1 Nephrin-like protein 1
Molecular Weight(MW)
83536 Da
Function
Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1 (By similarity)
Tissue Specificity
Abundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli
Cellular Localization
Cell membrane; Single-pass type I membrane protein (Potential). Note=Predominantly located at podocyte slit diaphragm
KIRREL Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the KIRREL antibody detected the KIRREL protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.