Application
LAMP2 Antibody (N-term) (Cat. #AM1851a) western blot analysis in mouse NIH-3T3 cell line lysates (15ug/lane).This demonstrates the LAMP2 antibody detected the LAMP2 protein (arrow).Application
LAMP2 Monoclonal (ascites) (Cat. #AM1851a) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LAMP2 Monoclonal (ascites) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | LAMP2 Antibody (Ascites) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LAMP2; Lysosome-associated membrane glycoprotein 2; CD107 antigen-like family member B; CD_antigen=CD107b; Flags: Precursor |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 157CT16.6.6 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:16000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | LAMP2 Lysosome-associated membrane glycoprotein 2 CD107 antigen-like family member B CD_antigen=CD107b Flags: Precursor |
|---|---|
| Molecular Weight(MW) | 44961 Da |
| Function | Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens |
| Tissue Specificity | Isoform LAMP-2A is highly expressed in placenta, lung and liver, less in kidney and pancreas, low in brain and skeletal muscle. Isoform LAMP-2B is highly expressed in skeletal muscle, less in brain, placenta, lung, kidney and pancreas, very low in liver |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein Lysosome membrane; Single-pass type I membrane protein. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane |
| Entrez Gene | 3920 |
|---|---|
| Nucleotide Accession | NP_054701.1 |
Application
LAMP2 Antibody (N-term) (Cat. #AM1851a) western blot analysis in mouse NIH-3T3 cell line lysates (15ug/lane).This demonstrates the LAMP2 antibody detected the LAMP2 protein (arrow).
Application
LAMP2 Monoclonal (ascites) (Cat. #AM1851a) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LAMP2 Monoclonal (ascites) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:16000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | LAMP2 mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
