Application
Western blot analysis on (A) Jurkat, (B) HepG2 and (C) HuT-78 cell lysates using anti-Lipin-1 RabMAb (Cat. #AJ1446a).Application
Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-Lipin1 RabMAb (Cat. #AJ1446a).Application
Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-Lipin1 RabMAb (Cat. #AJ1446a).Application
Immunofluorescent staining of HepG2 cells using anti-Lipin1 RabMAb (Cat. #AJ1446a).| Product Name | Lipin-1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR3725 |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:20000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0188 |
|---|---|
| Molecular Weight(MW) | 98664 Da |
| Function | Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A/PPARA to modulate lipid metabolism gene expression (By similarity). Is involved in adipocyte differentiation. May also be involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol (By similarity) |
| Tissue Specificity | Specifically expressed in skeletal muscle. Also abundant in adipose tissue. Lower levels in some portions of the digestive tract |
| Cellular Localization | Nucleus membrane (By similarity). Cytoplasm, cytosol (By similarity). Endoplasmic reticulum membrane (By similarity) |
| Entrez Gene | 23175 |
|---|
Application
Western blot analysis on (A) Jurkat, (B) HepG2 and (C) HuT-78 cell lysates using anti-Lipin-1 RabMAb (Cat. #AJ1446a).
Application
Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-Lipin1 RabMAb (Cat. #AJ1446a).
Application
Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-Lipin1 RabMAb (Cat. #AJ1446a).
Application
Immunofluorescent staining of HepG2 cells using anti-Lipin1 RabMAb (Cat. #AJ1446a).| Application Notes | WB:1:20000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
