Application
Figure 1: Western blot analysis using anti-LPP mAb against Hela (1), NIH/3T3 (2), COS (3), Caki (4), MCF-7 (5), HepG2 (6) and SMMC-7721 (7) cell lysate.Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human small intestine using anti-LPP mAb with DAB staining.Application
Figure 3: Immunohistochemical analysis of paraffin-embedded human vessels tissues using anti-LPP mAb.| Product Name | LPP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 8B3A11 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:500 - 2000. IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | LPP |
|---|---|
| Molecular Weight(MW) | 65746 Da |
| Function | May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus |
| Tissue Specificity | Expressed in a wide variety of tissues but no or very low expression in brain and peripheral leukocytes |
| Cellular Localization | Nucleus. Cytoplasm. Cell junction. Cell membrane. Note=Found in the nucleus, in the cytoplasm and at cell adhesion sites. Shuttles between the cytoplasm and the nucleus. It has been found in sites of cell adhesion such as cell-to-cell contact and focal adhesion which are membrane attachment sites of cells to the extracellular matrix. Mainly nuclear when fused with HMGA2/HMGIC and MLL |
| Entrez Gene | 4026 |
|---|---|
| Nucleotide Accession | NP_005569.1 |
Application
Figure 1: Western blot analysis using anti-LPP mAb against Hela (1), NIH/3T3 (2), COS (3), Caki (4), MCF-7 (5), HepG2 (6) and SMMC-7721 (7) cell lysate.
Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human small intestine using anti-LPP mAb with DAB staining.
Application
Figure 3: Immunohistochemical analysis of paraffin-embedded human vessels tissues using anti-LPP mAb.| Application Notes | WB:1:500 - 2000. IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of human LPP expressed in E. Coli. |
