Application
LRRC26 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the LRRC26 antibody detected the LRRC26 protein (arrow).| Product Name | LRRC26 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CAPC |
|---|---|
| Alternative Names | LRRC26 CAPC Leucine-rich repeat-containing protein 26 BK channel auxilliary gamma subunit LRRC26 Cytokeratin-associated protein in cancer |
| Molecular Weight(MW) | 34857 Da |
| Function | Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels from a high-voltage to a low- voltage activated channel type in non-excitable cells. These are characterized by negative membrane voltages and constant low levels of calcium |
| Tissue Specificity | Isoform 1 is expressed highly in normal prostate and salivary gland, very weakly in colon, pancreas, and intestine, and not at all in other tissues. Isoform 1 is expressed highly in many cancer cell lines and in breast cancer, pancreatic cancer and colon cancer. Isoform 2 is expressed in cancer cell lines |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. Note=Localizes to the cytoplasm when expressed at high levels (PubMed:15164053) |
| Entrez Gene | 389816 |
|---|---|
| Nucleotide Accession | NP_001013675.1 |
Application
LRRC26 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the LRRC26 antibody detected the LRRC26 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
