Application
Immunohistochemical staining of adult mouse retina showing specific immunolabeling of the ABCA4 protein using ABCA4 (Rim Protein) antibody [3F4] .| Product Name | ABCA4 (Rim Protein) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [3F4] to ABCA4 (Rim Protein)May play a role in photoresponse. Retinoids, and most likely retinal, are the natural substrates for transport by abcr in rod outer segments. May act in the visual cycle to flip PE-all-trans-retinal adducts from the lumenal to the cytosolic face of the disk membrane, move free all-trans-retinal from the lipid phase of the disk membrane to a juxtamembrane location, or possibly reorient all-trans-retinal in the bilayer. |
| Immunogen | Partially purified bovine 220-kDa disc rim protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Clone Number | 3F4 |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| Optimal working dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | HumanMouseXenopusBovine |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Synonyms | ATPbinding cassette subfamily A (ABC1) member4 ATP-binding cassette sub-family A (ABC1) member 4 STGD ARMD2 FFM STGD1 ABCR FLJ17534 RMP ATPbinding cassette subfamily A (ABC1) member 4 DKFZp781N1972 RP19 CORD3 ABCA4 ABC10 |
|---|---|
| Target | ABCA4 (Rim Protein) |
| Molecular Weight(MW) | 220 (note) |
Application
Immunohistochemical staining of adult mouse retina showing specific immunolabeling of the ABCA4 protein using ABCA4 (Rim Protein) antibody [3F4] .| Application Notes | Optimal working dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For long-term storage, aliquot and store at -20 C. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
