Mouse Monoclonal antibody [MRP8 7C12/4] to ABCC11MRP-8 and MRP-14 are cytosolic calcium-binding proteins of 8kDa and 14kDa that form a heterodimer. MRP-8 and MRP-14 are expressed in peripheral blood monocytes, neutrophils and keratinocytes (mature). Expression is lost on tissue maturation of monocytes to macrophages. MRP-14 may be associated with monocyte and neutrophil activation and the accumulation of these cells in inflammatory sites.
Immunogen
recombinant Human MRP8
Key Feature
Clonality
Monoclonal
Isotype
IgM
Clone Number
MRP8 7C12/4
Host Species
Mouse
Tested Applications
ELISAFACSWB
ELISA: Use at an assay dependent dilution. FACS: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 8 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Target Information
Gene Synonyms
85320 MRP8 607040 Q96J66 ABCC11
Target
ABCC11
Positive Control
Neutrophil lysate (particularly neutrophils from spleen).
Application Notes
ELISA: Use at an assay dependent dilution. FACS: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 8 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.