Application
at a 1/500 dilution staining approximately 81 kDa human ABCG 8 by Western blot (ECL). A= Mouse liver microsomes from G5/8 knockout. B = Wild type. C = Mice expressing G5/8 transgenes.| Product Name | ABCG8 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Polyclonal anti - ABCG8 ( ATP Binding cassette transporter )ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols. The mutated form of this transporter can lead to sterol accumulation and atherosclerosis or sitosterolemia, a rare autosomal recessive disorder, characterized by hyperabsorption of sterols and the inability to excrete sterols into bile. |
| Immunogen | A synthetic peptide from the n-terminal region of human ABCG8 protein. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Not tested in other applictions. Dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Gene Synonyms | Q9H221 ABCG8 210250 sterolin2 sterolin 2 64241 |
|---|---|
| Target | ABCG8 |
| Tissue Specificity | Specific for ABCG8. |
Application
at a 1/500 dilution staining approximately 81 kDa human ABCG 8 by Western blot (ECL). A= Mouse liver microsomes from G5/8 knockout. B = Wild type. C = Mice expressing G5/8 transgenes.| Application Notes | Not tested in other applictions. Dilutions/concentrations should be determined by the researcher.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
