Mouse monoclonal [M4110421] to Angiotensin Converting EnzymeAngiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system.
Immunogen
Human Angiotensin Converting Enzyme
Key Feature
Clonality
Monoclonal
Isotype
IgM
Clone Number
M4110421
Host Species
Mouse
Tested Applications
ELISAFACSIHC-FIHC-P
ELISA: Use at an assay dependent dilution. FACS: Use at an assay dependent dilution. IHC-P: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
HumanMouseBovine
Concentration
1mg/ml
Target Information
Target
ACE
Tissue Specificity
Shown to crossreact with human, bovine and mouse Angiotensin Converting Enzyme and Endothelial cells.
Cellular Localization
Type I membrane protein
Application Notes
ELISA: Use at an assay dependent dilution. FACS: Use at an assay dependent dilution. IHC-P: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.