Application
Western blot analysis of extracts from HeLa/293/COLO/A549 cells, using CHRNA10 Antibody. The lane on the right is treated with the synthesized peptide.| Product Name | AChR alpha 10 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to AChR alpha 10Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CHRNA10. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ELISA: 1:20000Optimal dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Neuronal acetylcholine receptor subunit alpha-10 Neuronal acetylcholine receptor subunit alpha10 Nicotinic acetylcholine receptor subunit alpha10 Nicotinic acetylcholine receptor subunit alpha 10 NACHR alpha10 CHRNA10 NACHR alpha 10 |
|---|---|
| Target | AChR alpha 10 |
| Molecular Weight(MW) | 49 kDa (note) |
| Tissue Specificity | CHRNA10 Antibody detects endogenous levels of total CHRNA10 protein. |
Application
Western blot analysis of extracts from HeLa/293/COLO/A549 cells, using CHRNA10 Antibody. The lane on the right is treated with the synthesized peptide.| Application Notes | ELISA: 1:20000Optimal dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
