Application
Activin A Receptor type I antibody detects ACVR1 protein at membrane on Cal27 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded Cal27 xenograft. Activin A Receptor type I antibody dilution: 1:500.Application
Activin A Receptor type I antibody detects Activin A Receptor type I protein at membrane on mouse prostate by immunohistochemical analysis. Sample: Paraffin-embedded mouse prostate. Activin A Receptor type I antibody dilution: 1:500. Scale bar = M μm.| Product Name | Activin A Receptor type I antibody |
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| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Activin A Receptor type I (activin A receptor, type I)Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Activin A Receptor type I. The exact sequence is proprietary. |
| Clonality | Polyclonal |
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| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | HumanMouse |
| Predicted Reactivity | Rat, Xenopus laevis, Rhesus Monkey, BovineRat (99%), Xenopus laevis (93%), Rhesus Monkey (100%), Bovine (100%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ACTRI antibody ACVR1A antibody ACVRLK2 antibody ALK2 antibody FOP antibody SKR1 antibody TSRI antibody ACVR1 antibody serine/threonine-protein kinase receptor R1 antibody activin receptor type I antibody TGF-B superfamily receptor type I antibody |
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| Molecular Weight(MW) | 57 kDa (note) |
| Cellular Localization | Membrane |
Application
Activin A Receptor type I antibody detects ACVR1 protein at membrane on Cal27 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded Cal27 xenograft. Activin A Receptor type I antibody dilution: 1:500.
Application
Activin A Receptor type I antibody detects Activin A Receptor type I protein at membrane on mouse prostate by immunohistochemical analysis. Sample: Paraffin-embedded mouse prostate. Activin A Receptor type I antibody dilution: 1:500. Scale bar = M μm.| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
