Application
Mouse tissue extract (50 µg) was separated by 10% SDS-PAGE, and the membrane was blotted with Activin A Receptor type I antibody diluted at 1:500.Application
Activin A Receptor type I antibody detects Activin A Receptor type I protein by immunohistochemical analysis. Sample: Frozen sectioned adult mouse retina. Green: Activin A Receptor type I protein stained by Activin A Receptor type I antibody diluted at 1:250. Red: Protein kinase C alpha staining. Blue: Fluoroshield with DAPI .Application
Activin A Receptor type I antibody detects ACVR1 protein by Western blot analysis. A. 50 µg rat liver lysate/extract 7.5 % SDS-PAGE Activin A Receptor type I antibody dilution: 1:1000| Product Name | Activin A Receptor type I antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Activin A Receptor type I (activin A receptor, type I)Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Activin A Receptor type I. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-FWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
|
| Species Reactivity | MouseRat |
| Predicted Reactivity | Human, Xenopus laevis, Rhesus Monkey, BovineHuman (100%), Xenopus laevis (93%), Rhesus Monkey (100%), Bovine (100%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ACTRI antibody ACVR1A antibody ACVRLK2 antibody ALK2 antibody FOP antibody SKR1 antibody TSRI antibody ACVR1 antibody serine/threonine-protein kinase receptor R1 antibody activin receptor type I antibody TGF-B superfamily receptor type I antibody |
|---|---|
| Molecular Weight(MW) | 57 kDa (note) (3) |
| Cellular Localization | Membrane |
Application
Mouse tissue extract (50 µg) was separated by 10% SDS-PAGE, and the membrane was blotted with Activin A Receptor type I antibody diluted at 1:500.
Application
Activin A Receptor type I antibody detects Activin A Receptor type I protein by immunohistochemical analysis. Sample: Frozen sectioned adult mouse retina. Green: Activin A Receptor type I protein stained by Activin A Receptor type I antibody diluted at 1:250. Red: Protein kinase C alpha staining. Blue: Fluoroshield with DAPI .
Application
Activin A Receptor type I antibody detects ACVR1 protein by Western blot analysis. A. 50 µg rat liver lysate/extract 7.5 % SDS-PAGE Activin A Receptor type I antibody dilution: 1:1000| Positive Control | mouse heart , rat liver |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
