| Product Name | ADAM17 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [8C13] to ADAM17This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant ADAM17 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 8C13 |
| Host Species | Mouse |
| Tested Applications | FACSWB |
| WB(1:500-1000)|FC(1:20-100): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ADAM18 TACE CD156B NISBD CSVP ADAM metallopeptidase domain 17 |
|---|---|
| Target | ADAM17 |
| Tissue Specificity | This antibody was selected for its ability to detect human ADAM17 |
| Application Notes | WB(1:500-1000)|FC(1:20-100): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
