Mouse monoclonal [30D445.1] to ADAMTSL1ADAMTSL1 is a secreted molecule, expressed in adult skeletal muscle, resembling members of the ADAMTS family of proteases, containing four thrombospondin type I repeats. Human ADAMTSL1 cleaves aggrecan and is thereby classified as an 'aggrecanase'. Like the ADAMTS proteases, each domain in ADAMTSL1 has an even number of cysteine residues suggesting that each domain may have internal disulfide bonds and that punctin consists of a series of independently folded and disulfide-bonded domains.
Immunogen
Synthetic peptide (Human).
Key Feature
Clonality
Monoclonal
Isotype
IgM
Clone Number
30D445.1
Host Species
Mouse
Tested Applications
WB
WB: Use at a dilution of 1/250 - 1/500. Detects a band of approximately 60 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
92949 609198 ADAMTSL1 Q8N6G6 MGC40193 ADAMTSR1
Target
ADAMTSL1
Cellular Localization
Secreted. Associated with the extracellular matrix.
Application
Application
Western Blot analysis of ADAMTSL1 using at a 1:250 dilution against human heart.
Positive Control
Human muscle cell lysate.
Application Notes
WB: Use at a dilution of 1/250 - 1/500. Detects a band of approximately 60 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.