| Product Name | alpha 1 Fetoprotein receptor antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [5E1] to alpha 1 Fetoprotein ReceptorThis gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq] |
| Immunogen | Full length native protein (purified) (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | 5E1 |
| Host Species | Mouse |
| Tested Applications | ICC/IF |
| Blocking alpha-fetoprotein and its receptor.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | HPAFP 174 FETA 104150 AFP alpha1 Fetoprotein receptor alpha 1 Fetoprotein receptor P02771 |
|---|---|
| Target | alpha 1 Fetoprotein receptor |
| Tissue Specificity | Reacts with different determinants of human alpha-fetoprotein receptor. |
| Positive Control | The following cultured tumor cells were used as positive controls: ovarian adenocarcinoma SKOV3, human mammary carcinoma MCF-7, human cervical carcinoma Hela, B-cell lymphoma Raji and T-cell lymphoma Jurkat. Negative immunoreactivity with AFP receptor sho |
|---|---|
| Application Notes | Blocking alpha-fetoprotein and its receptor.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. We recommend to parafilm vials during storage to prevent evaporation of buffer. |
| Storage Buffer | PBS with 0.1% sodium azide, pH 7.4 |
