| Product Name | Alpha fetoprotein / AFP antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [C3] to alpha FetoproteinThis is a major plasma protein produced by the yolk sac and the liver during fetal life. alpha Fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha Fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha Fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. alpha Fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha Fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |
| Immunogen | BALB/C mice were injected with purified human alpha-fetoprotein. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | C3 |
| Host Species | Mouse |
| Tested Applications | IHC-P |
| IHC-P: 1/25 - 1/50. An incubation period of 30 minutes at room temperature is recommended. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanDogPig |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | HPAFP 174 FETA 104150 alpha Fetoprotein AFP P02771 |
|---|---|
| Target | alpha Fetoprotein |
| Cellular Localization | Cytoplasmic |
| Positive Control | Fetal liver |
|---|---|
| Application Notes | IHC-P: 1/25 - 1/50. An incubation period of 30 minutes at room temperature is recommended. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | Preservative: Sodium Azide |
