Application
Western blot analysis of alpha Fodrin cleaved form using )| Product Name | alpha Fodrin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to alpha FodrinFodrin is a universally expressed membrane-associated cytoskeletal protein consisting of alpha and beta subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. Alpha Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases generating N-terminal 150 kDa, C-terminal 120 kDa, and 35 kDa major products. Cleavage of alpha Fodrin leads to membrane malfunction and cell shrinkage. |
| Immunogen | Available on request. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-FWB |
| IHC-Fr: Use at a concentration of 10 - 20 μg/ml. WB: Use at a concentration of 1.0 μg/ml. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Q13813 SPTAN1 alpha Fodrin (ALPHA)IISPECTRIN 182810 6709 (ALPHA)II-SPECTRIN (ALPHA)II SPECTRIN |
|---|---|
| Target | alpha Fodrin |
| Tissue Specificity | This antibody recognizes the 240 kDa full length and 150 kDa N-terminal fragment of alpha Fodrin. |
Application
Western blot analysis of alpha Fodrin cleaved form using )| Application Notes | IHC-Fr: Use at a concentration of 10 - 20 μg/ml. WB: Use at a concentration of 1.0 μg/ml. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS pH7.2 with 50% glycerol, 1% BSA and 0.02% sodium azide |
