Application
Immunofluorescence of SNCA in rat brain tissue with SNCA antibody at 20 ug/ml.Application
Western blot analysis of SNCA in mouse cerebellum tissue lysate with SNCA antibody at 1 ug/ml.Application
Immunohistochemistry of SNCA in rat brain tissue with SNCA antibody at 5 ug/ml.| Product Name | alpha Synuclein antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to alpha SynucleinAlpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009] |
| Immunogen | SNCA antibody was raised against a 19 amino acid peptide near the carboxy terminus of human SNCA. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-PWB |
| WB: 1 - 2 ug/ml. IHC-P: 5 ug/mL. IF: 20 ug/ml: |
|
| Species Reactivity | MouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | PARK1 synuclein alpha (non A4 component of amyloid precursor) PARK4 PD1 NACP SNCA |
|---|---|
| Target | alpha Synuclein |
| Tissue Specificity | SNCA antibody is mouse and rat reactive. At least three isoforms of SNCA are known to exist. |
Application
Immunofluorescence of SNCA in rat brain tissue with SNCA antibody at 20 ug/ml.
Application
Western blot analysis of SNCA in mouse cerebellum tissue lysate with SNCA antibody at 1 ug/ml.
Application
Immunohistochemistry of SNCA in rat brain tissue with SNCA antibody at 5 ug/ml.| Application Notes | WB: 1 - 2 ug/ml. IHC-P: 5 ug/mL. IF: 20 ug/ml: |
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| Form | Liquid |
|---|---|
| Storage Instructions | Be stored at 4oC for three months and -20oC, stable for up to one year. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
