Rabbit Polyclonal antibody to ALS2CR2This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Immunogen
ILPIP antibody was raised against a synthetic peptide corresponding to amino acids near the center of human ILPIP.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIHC-PWB
IHC-P: 10 ug/mL:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Immunohistochemistry of ILPIP in human brain tissue with ILPIP antibody at 10 ug/mL.
Application
Western blot analysis of ILPIP in human brain lysate with ILPIP antibody at (A) 1 and (B) 2 ug/mL.
Application Notes
IHC-P: 10 ug/mL:
Additional Information
Form
Liquid
Storage Instructions
Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.