Application
WB analysis of rat Liver lysate using AMACR antibody at a dilution of 1:1,000.| Product Name | AMACR antibody [2F3-C11-B12] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [2F3-C11-B12] to AMACRThis gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)-and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. |
| Immunogen | Purified recombinant human AMACR(C-terminus) protein fragments expressed in E.coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 2F3-C11-B12 |
| Host Species | Mouse |
| Tested Applications | ICC/IFWB |
| Species Reactivity | Rat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CBAS4 , AMACRD , alpha-methylacyl-CoA racemase , RACE , RM |
|---|---|
| Target | AMACR |
| Molecular Weight(MW) | 42kDa (note) |
| Cellular Localization | Peroxisome. Mitochondrion |
Application
WB analysis of rat Liver lysate using AMACR antibody at a dilution of 1:1,000.| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol |
