Application
IHC-P analysis of human pancreas tissue using Amylin antibody [R10/99].| Product Name | Amylin antibody [R10/99] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [R10/99] to AmylinIslet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. [provided by RefSeq, Apr 2011] |
| Immunogen | CATQRLANFLV coupled to tuberculin |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | R10/99 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHC-FIHC-P |
| Immunohistology - Frozen: Max Dilution 1/100 | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Gene Synonyms | IAP , IAPP , DAP , islet amyloid polypeptide |
|---|---|
| Target | Amylin |
| Tissue Specificity | This antibody recognizes the islet amyloid polypeptide (amylin). |
Application
IHC-P analysis of human pancreas tissue using Amylin antibody [R10/99].| Application Notes | Immunohistology - Frozen: Max Dilution 1/100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | 0.09%Sodium Azide |
