Application
Western blot analysis of extracts of various cell lines, using ANAPC5 antibody.Application
Immunohistochemistry of paraffin-embedded human kidney using ANAPC5 antibody at dilution of 1:100 (x400 lens).Application
Immunohistochemistry of paraffin-embedded rat kidney using ANAPC5 antibody at dilution of 1:100 (x400 lens).| Product Name | ANAPC5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to ANAPC5This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008] |
| Immunogen | Recombinant protein of human ANAPC5 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCIHC-PWB |
| WB: 1:500 - 1:2000. IHC: 1:50 - 1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | anaphase promoting complex subunit 5 , APC5 |
|---|---|
| Target | ANAPC5 |
Application
Western blot analysis of extracts of various cell lines, using ANAPC5 antibody.
Application
Immunohistochemistry of paraffin-embedded human kidney using ANAPC5 antibody at dilution of 1:100 (x400 lens).
Application
Immunohistochemistry of paraffin-embedded rat kidney using ANAPC5 antibody at dilution of 1:100 (x400 lens).| Application Notes | WB: 1:500 - 1:2000. IHC: 1:50 - 1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
