| Product Name | Angiopoietin 1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [26B10] to Angiopoietin 1Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010] |
| Immunogen | human recombinant Ang1 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 26B10 |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| Western blotting(1:1000-2000)|Immunohistochemistry(1:50-400): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | AGPT ANGPT1 ANG1 angiopoietin 1 AGP1 |
|---|---|
| Target | Angiopoietin-1 |
| Tissue Specificity | This antibody recognizes human Ang1 in western blot without cross reactivity with human Ang2. |
| Application Notes | Western blotting(1:1000-2000)|Immunohistochemistry(1:50-400): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
