Application
WB analysis of mouse kidney lysate using ACE antibody at a dilution of 1:1,000.| Product Name | Angiotensin Converting Enzyme 1 antibody [4F3-E6-H8] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [4F3-E6-H8] to Angiotensin Converting Enzyme 1This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. |
| Immunogen | The immunogen corresponding to a region within amino acids 198 and 481 of Human Angiotensin Converting Enzyme 1. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | 4F3-E6-H8 |
| Host Species | Mouse |
| Tested Applications | WB |
| Species Reactivity | Mouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ACE , DCP , ACE1 , DCP1 , ICH , angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 , MVCD3 , CD143 |
|---|---|
| Target | Angiotensin Converting Enzyme 1 |
| Molecular Weight(MW) | 190kDa (note) |
| Cellular Localization | Angiotensin-converting enzyme, soluble form: Secreted. Cell membrane; Single-pass type I membrane protein. |
Application
WB analysis of mouse kidney lysate using ACE antibody at a dilution of 1:1,000.| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol |
