Rabbit polyclonal antibody to Annexin VIIIThe annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain which binds to phospholipids in a Ca2+-dependent manner. Annexin family members have been implicated as regulators of diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. Annexin VIII is preferentially expressed in acute promyelocytic leukemia (APL) cells which may relate its role in hematopoietic cell differentiation.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate can be used as a positive control. The antibody detects 36 kDa annexin VIII of human origin. The ~28-30 kDa cleavage fragments can also be detected in Jurkat cell lysate:
Species Reactivity
Human
Concentration
0.5mg/ml
Target Information
Gene Synonyms
ANXA7 Annexin A7 ANX7 SNX
Target
Annexin VIII
Tissue Specificity
This antibody is specific for Annexin VIII.
Application
Application
Western blot analysis of Annexin VIII expression in Jurkat cell lysate.
Application Notes
Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate can be used as a positive control. The antibody detects 36 kDa annexin VIII of human origin. The ~28-30 kDa cleavage fragments can also be detected in Jurkat cell lysate:
Additional Information
Form
Liquid
Storage Instructions
The antibody solution should be gently mixed before use. Stored at -20 °C for future use.