Application
ApplicationApplication
Human Colon Carcinoma stained with anti-Adenomatous Polyposis Coli (APC) antibodyApplication
ab15271 staining APC in colon carcinoma by Immunohistochemistry (FFPE-sections).| Product Name | APC antibody (ready-to-use) |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to APC predilutedThis gene encodes a tumor suppressor protein that includes among its many intracellular functions one of nuclear export. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. |
| Immunogen | Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (C terminal). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCIHC-P |
| IHC-P: Ready to use for 10 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Optimal dilutions/concentrations should be determined by the end user. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | DP2.5, 324, FAP, DP3, GS, 135290, DP2, P25054, APC, FPC |
|---|---|
| Target | APC |
Application
Application
Application
Human Colon Carcinoma stained with anti-Adenomatous Polyposis Coli (APC) antibody
Application
ab15271 staining APC in colon carcinoma by Immunohistochemistry (FFPE-sections).| Positive Control | Colon carcinoma. |
|---|---|
| Application Notes | IHC-P: Ready to use for 10 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Optimal dilutions/concentrations should be determined by the end user. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution and store at 4°C. Do not freeze. |
| Storage Buffer | PBS, pH 7.4 containing 1%BSA and 0.1% sodium azide |
