Mouse monoclonal antibody [1609] to Apolipoprotein BApolipoprotein B consists of a single polypeptide chain with a molecular weight of 549 kDa and is mostly synthesised in the liver. It is a major apolipoprotein of very low density, intermediate density and low density lipoproteins (LDL) as well as being a major component of lipoprotein (a). Apolipoprotein B is a ligand for the LDL receptor and elevated levels are associated with premature atherosclerosis. Normal plasma apolipoprotein B levels are around 800mg/L.
Immunogen
Full length native LDL (purified from human serum).
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1609
Host Species
Mouse
Tested Applications
EIARIA
EIA: Use at an assay dependent dilution. RIA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
338, FLDB, P04114, APOB, 107730, Apo B
Target
Apolipoprotein B
Tissue Specificity
does not cross-react with Apo A I or Apo A II.
Cellular Localization
Secreted
Application Notes
EIA: Use at an assay dependent dilution. RIA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.