Application
Western blot analysis of Amyloid Precursor Protein expression in mouse brain using APP mAb (3E9)| Product Name | APP antibody [3E9] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [3E9] to APPAmyloid Precursor Protein (APP) functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1; APP is rapidly internalized via clathrin-coated pits. APP is important for neurite growth, neuronal adhesion and axonogenesis. |
| Immunogen | Synthetic peptide: LEVPTDGNAGLLAEPQIAMFC , corresponding to amino acids 18-38 of Human Amyloid Precursor Protein. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 3E9 |
| Host Species | Mouse |
| Tested Applications | IHC-PWB |
| IHC-P: Use at a concentration of 5 - 10 μg/ml. WB: Use at a concentration of 5 - 10 μg/ml. Predicted molecular weight: 87 kDa. Optimal dilutions/concentrations should be determined by the end user. | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein A |
| Gene Synonyms | AD1, APP, ABETA, CTFgamma, APPI, 351, ABPP, Amyloid Precursor Protein, CVAP, PN2, 104760, P05067, AAA |
|---|---|
| Target | APP |
| Cellular Localization | Endoplasmic reticulum, Golgi Apparatus, Cytoplasmic, Cell Membrane. |
Application
Western blot analysis of Amyloid Precursor Protein expression in mouse brain using APP mAb (3E9)| Application Notes | IHC-P: Use at a concentration of 5 - 10 μg/ml. WB: Use at a concentration of 5 - 10 μg/ml. Predicted molecular weight: 87 kDa. Optimal dilutions/concentrations should be determined by the end user. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: NoneConstituents: PBS, 10mg/ml Sucrose |
