| Product Name | APRIL antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to APRILMembers in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for a proliferation-inducing ligand), TALL-2 (for TNF- and ApoL-related Leukocyte-expressed Ligand 2), and TRDL-1 alpha (for TNF related death ligand1 alpha) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer. |
| Immunogen | Synthetic peptide, corresponding to amino acids 67-79 of Human APRIL. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB: Use at a concentration of 4-5 μg/ml. Predicted molecular weight: 27 kDa. Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | 8741, TNFSF13, 604472, UNQ383/PRO715, ligand, O75888, TRDL1, APRIL, TALL2, TRDL-1, TRDL 1 |
|---|---|
| Target | APRIL |
| Cellular Localization | Secreted |
| Positive Control | HL60 and Jurkat cell lysate. |
|---|---|
| Application Notes | For WB: Use at a concentration of 4-5 μg/ml. Predicted molecular weight: 27 kDa. Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Upon Receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS, pH 7.4 with 0.02% sodium azide as preservative. |
