| Product Name | APRIL antibody [Aprily-1] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [Aprily-1] to APRILMembers in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer. |
| Immunogen | Recombinant human APRIL corresponding to amino acids 93-233, expressed in bacteria. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | Aprily-1 |
| Host Species | Mouse |
| Tested Applications | FACSWB |
| For FACS: Use at a concentration of 10 μg/ml. This antibody also works for intracellular FC staining. For WB: Use at a concentration of 1 μg/ml. Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Unpurified |
| Gene Synonyms | 8741, TNFSF13, 604472, UNQ383/PRO715, ligand, O75888, TRDL1, APRIL, TALL2, TRDL-1, TRDL 1 |
|---|---|
| Target | APRIL |
| Application Notes | For FACS: Use at a concentration of 10 μg/ml. This antibody also works for intracellular FC staining. For WB: Use at a concentration of 1 μg/ml. Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon Receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline containing 0.02% sodium azide |
