Rabbit polyclonal antibody to AquariusIntron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
Immunogen
Synthetic peptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
1:500 for WB
Species Reactivity
Mouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
KIAA0560
Target
Aquarius
Application
Application
Western blot of binding protein Aquarius using antibody 1:500 in diluObuffer. Apparent MW of AQR is 140kDa.
Application Notes
1:500 for WB
Additional Information
Form
Liquid
Storage Instructions
Product should be aliquoted and stored at -20∞C. Avoid repeated freeze/thaw cycles.