Application
Western blot analysis of Asb-2 in HL60 cell lysate at 1:1000.| Product Name | ASB2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to ASB2The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain ""SOCS boxes"" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known. |
| Immunogen | Synthetic peptides corresponding to amino acids 75-93 and 348-368 of Human ASB2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: Use at a dilution of 1/500 - 1/1000. Predicted molecular weight: 70 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Synonyms | ASB2 MGC40044 51676 605759 ASB-2 Q96Q27 ASB 2 |
|---|---|
| Target | ASB2 |
| Cellular Localization | Cytoplasmic |
Application
Western blot analysis of Asb-2 in HL60 cell lysate at 1:1000.| Positive Control | Human spleen lysate |
|---|---|
| Application Notes | WB: Use at a dilution of 1/500 - 1/1000. Predicted molecular weight: 70 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.02% Sodium Azide; Constituents: PBS |
