Application
Western blot analysis of extracts from COLO205 cells, using ATF6B Antibody. The lane on the right is treated with the synthesized peptide.| Product Name | ATF6B antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to ATF6BTranscriptional factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER stress. Binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAATN(9)CCAC[GA]-3') when NF-Y is bound to ERSE. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ATF6B. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ELISA: 1:20000Optimal dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ATF6B c cAMP response element-binding protein-related protein Activating transcription factor 6 beta ATF6-beta cAMP response elementbinding proteinrelated protein cAMP-responsive element-binding protein-like 1 Crebrp ATF6beta Protein G13 Activati |
|---|---|
| Target | ATF6B |
| Molecular Weight(MW) | 76 kDa (note) |
| Tissue Specificity | ATF6B Antibody detects endogenous levels of total ATF6B protein. |
| Cellular Localization | Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus. |
Application
Western blot analysis of extracts from COLO205 cells, using ATF6B Antibody. The lane on the right is treated with the synthesized peptide.| Application Notes | ELISA: 1:20000Optimal dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
