Application
Immunofluorescence of ATP11B in K562 cells with ATP11B antibody at 20 μg/mL.| Product Name | ATP11B antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to ATP11BATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IF |
| ICC/IF:1:200~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ATP11B ATPIR ATPase class VI type11B ATPase class VI type 11B ATPIF |
|---|---|
| Target | ATP11B |
| Tissue Specificity | This antibody is specific for ATP11B |
Application
Immunofluorescence of ATP11B in K562 cells with ATP11B antibody at 20 μg/mL.| Positive Control | Blocking Peptide: Cat.No. GTX85003-PEP - ATP11B Peptide Lysates: Cat. No. GTX27911 - K562 Cell Lysate |
|---|---|
| Application Notes | ICC/IF:1:200~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Antibody is supplied in PBS containing 0.02% sodium azide |
