Rabbit Polyclonal antibody to AXL (AXL receptor tyrosine kinase)The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human AXL. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, PigMouse (83%), Rat (83%), Pig (83%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
AXL antibody AXL antibody AXL receptor tyrosine kinase antibody JTK11 antibody UFO antibody
Target
AXL
Molecular Weight(MW)
98 kDa (note) (2)
Cellular Localization
Membrane; Single-pass type I membrane protein
Application
Application
Various whole cell extracts (30 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with AXL antibody diluted at 1:1000.
Positive Control
A549 , H1299
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.