| Product Name | BACE1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [61-3E7] to BACE1Alzheimer's disease (AD) is characterized by the progressive formation in the brain of insoluble amyloid plaques and vascular deposits consisting of the 4-kD amyloid b-peptide (Ab). Ab generation is initiated by proteolytic cleavage of the amyloid precursor protein (APP) at the N-terminal of Ab by beta-secretase. The Ab peptide is then released by proteolytic cleavage at its C-terminus by g-secretase. |
| Immunogen | C-terminal peptide conjugated to thyroglobulin |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 61-3E7 |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| For WB: Use at 1 µg/mL: |
|
| Species Reactivity | HumanMouseMonkeyRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein A |
| Gene Synonyms | ASP2 BACE HSPC104 KIAA1149 beta-site APP-cleaving enzyme 1 BACE1 |
|---|---|
| Target | BACE1 |
| Application Notes | For WB: Use at 1 µg/mL: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Maintain at +2-8°C for 3 months or at -20°C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide |
