| Product Name | BACE1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [6J26] to BACE-1Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011] |
| Immunogen | The immunogen corresponding to a region within amino acids 22 and 460 of human BACE-1 (Uniport: P56817) |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 6J26 |
| Host Species | Mouse |
| Tested Applications | IHC-PWB |
|
For WB: Use at a dilution of 1:500-1:1000. : |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | BACE1 ASP2 beta-site APP-cleaving enzyme 1 BACE HSPC104 |
|---|---|
| Target | BACE-1 |
| Tissue Specificity | This antibody was selected for its ability to detect human BACE-1 protein |
| Application Notes |
For WB: Use at a dilution of 1:500-1:1000. : |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
