| Product Name | Bcl rambo antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [Rocky - 2] to Bcl ramboBcl rambo shares common structural characteristics with other members of the anti-apoptotic Bcl2 family members, but differs from them at its C-terminus, where a 250 amino acid sequence preceeds the membrane anchor region. It also differs from other pro-apoptotic Bcl-2 family members in that its membrane anchor C-terminus region is responsible for its apoptotic activity, not its Bcl-2 homology motifs. Bcl rambo may promote the activation of caspase-3 and apoptosis. |
| Immunogen | Recombinant fragment, corresponding to C terminal amino acids 224 - 459 of Human Bcl rambo, fused at the N terminus to a tag. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | Rocky-2 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIPWB |
| ICC: Use at a dilution of 1/300. IF: Use at a dilution of 1/300. IP: Use at a dilution of 1/100. WB: Use at a dilution of 1/1000. Predicted molecular weight: 58 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | BCL-RAMBO Bcl rambo Q9BXK5 23786 BCL2L13 BCLRAMBO MIL1 |
|---|---|
| Target | Bcl rambo |
| Cellular Localization | Mitochondrial (isoform 2) and Nuclear (isoform 2 and 3) |
| Application Notes | ICC: Use at a dilution of 1/300. IF: Use at a dilution of 1/300. IP: Use at a dilution of 1/100. WB: Use at a dilution of 1/1000. Predicted molecular weight: 58 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.02% Sodium Azide; Constituents: PBS |
