Application
WB analysis of mouse brain, Raw264.7, MCF7 and PC12 lysates using beta Arrestin 1 antibody at a dilution of 1:500.| Product Name | beta Arrestin 1 antibody [1H4-F5-C11] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [1H4-F5-C11] to beta Arrestin 1Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones,neurotransmitters, or sensory signals.Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors.Besides the central nervous system,it is expressed at high levels in peripheral blood leukocytes,and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions.Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.[provided by RefSeq,Jan 2011] |
| Immunogen | Purified recombinant human ARRB1 protein fragments expressed in E.coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2b |
| Clone Number | 1H4-F5-C11 |
| Host Species | Mouse |
| Tested Applications | WB |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ARB1 , arrestin, beta 1 , ARR1 , ARRB1 |
|---|---|
| Target | beta Arrestin 1 |
| Molecular Weight(MW) | 50kDa (note) |
| Cellular Localization | Cytoplasm. Nucleus. Cell membrane. Membrane ＞ clathrin-coated pit. Cell projection ＞ pseudopodium. Cytoplasmic vesicle. |
Application
WB analysis of mouse brain, Raw264.7, MCF7 and PC12 lysates using beta Arrestin 1 antibody at a dilution of 1:500.| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine(pH 7.4,150 mM NaCl)with 0.02% sodium azide,0.1mg/mlBSA and 50% glycerol. |
