Application
Immunohistochemical analysis of paraffin-embedded human Placenta tissues using CTNNB1 mouse mAbApplication
Western blot analysis using CTNNB1 mAb against CTNNB1-hIgGFc transfected HEK293 cell lysate.Application
Flow cytometric analysis of A549 cells using anti-CTNNB1 mAb (green) and negative control (purple).Application
Figure 2:Immunofluorescence analysis of A549 (left) and SK-BR-3 (right) cells using anti-CTNNB1 mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.| Product Name | beta Catenin antibody [4D5] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [4D5] to beta CateninThe protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009] |
| Immunogen | The immunogen corresponding to human CTNNB1 expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 4D5 |
| Host Species | Mouse |
| Tested Applications | ELISAFACSICC/IFIHC-PWB |
| ELISA: 1/10000. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CTNNB , ARMADILLO , MRD19 , CTNNB1 |
|---|---|
| Target | beta Catenin |
| Molecular Weight(MW) | 85 kDa (note) |
Application
Immunohistochemical analysis of paraffin-embedded human Placenta tissues using CTNNB1 mouse mAb
Application
Western blot analysis using CTNNB1 mAb against CTNNB1-hIgGFc transfected HEK293 cell lysate.
Application
Flow cytometric analysis of A549 cells using anti-CTNNB1 mAb (green) and negative control (purple).
Application
Figure 2:Immunofluorescence analysis of A549 (left) and SK-BR-3 (right) cells using anti-CTNNB1 mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.| Application Notes | ELISA: 1/10000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4℃, for long term storage, store at -20℃. |
| Storage Buffer | Ascitic fluid containing 0.03% sodium azide. |
