Application
ICC/IF analysis of A431 cells using beta Catenin antibody [E247] at a dilution of 1:250.Application
IHC-P analysis of IHC analysis of human colon adenocarcinoma tissue using beta Catenin antibody [E247] at a dilution of 1:500.Application
IHC analysis of kidney carcinoma tissue using beta Catenin antibody [E247].| Product Name | beta Catenin antibody [E247] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit monoclonal antibody [E247] to beta CateninThe protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009] |
| Immunogen | Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to Human beta Catenin aa 1-100 (N terminal). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Clone Number | E247 |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIHC-FIHC-PIPWB |
| Species Reactivity | HumanMouseMonkeyRatHamsterSheepBovine |
| Concentration | 1mg/ml |
| Gene Synonyms | armadillo , MRD19 , CTNNB , CTNNB1 , catenin (cadherin-associated protein), beta 1, 88kDa |
|---|---|
| Target | beta Catenin |
Application
ICC/IF analysis of A431 cells using beta Catenin antibody [E247] at a dilution of 1:250.
Application
IHC-P analysis of IHC analysis of human colon adenocarcinoma tissue using beta Catenin antibody [E247] at a dilution of 1:500.
Application
IHC analysis of kidney carcinoma tissue using beta Catenin antibody [E247].| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS containing 50% Glycerol, 0.05% BSA and 0.01% Sodium azide. |
