| Product Name | beta Lactamase antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal to Beta LactamaseThe beta lactam antibiotics (penicillins and cephalosporins) are the most frequently used antimicrobial agents. All of the beta lactams are structurally related through the presence of a core beta lactam ring. Bacterial resistance to beta lactams continues to increase, primarily due to the production of beta lactamases. Beta lactamases catalyze the hydrolysis of the beta lactam bond, which destroys antibacterial activity. Bacteria that produce TEM type or SHV type beta lactamases have point mutations in structural genes that have extended the substrate specificity of these beta lactamases. As a result, many of the beta lactamase producing Gram negative pathogens have become multidrug resistant. |
| Immunogen | The immunogen was recombinant full-length TEM-1 type beta-lactamase with His tag at the 5’ end. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | ELISAWB |
| For ELISA: Use at a concentration of 10 - 20 μg/ml. For WB: Use at a concentration of 5 - 15 μg/ml. Predicted molecular weight: 31.5 kDa. (This is the molecular weight of the unprocessed precursor.) Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | FLJ14902, G24, 114294, LACTB, P83111, MRPL56, 608440, beta Lactamase |
|---|---|
| Target | beta Lactamase |
| Tissue Specificity | This antibody specifically recognizes TEM type beta lactamases. |
| Cellular Localization | Periplasmic. |
| Application Notes | For ELISA: Use at a concentration of 10 - 20 μg/ml. For WB: Use at a concentration of 5 - 15 μg/ml. Predicted molecular weight: 31.5 kDa. (This is the molecular weight of the unprocessed precursor.) Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon Receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS, pH 7.4 |
