Mouse monoclonal antibody [S40B-18] to BK channel BETA3MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. At least four transcript variants encoding four different isoforms have been found for this gene. [provided by RefSeq]
Immunogen
Fusion protein amino acids 1-49 (unique N-terminus) of mouse BKBeta3a
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
S40B-18
Host Species
Mouse
Tested Applications
IHCIPWB
We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).
Species Reactivity
HumanMouseRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Protein G
Target Information
Gene Synonyms
KCNMB3, KCNMB2, KCNMBL, HBETA3, BKBeta3
Target
BK channel BETA3
Molecular Weight(MW)
32 kDa (note)
Tissue Specificity
No cross-reactivity against BKBeta1, BKBeta1, BKBeta3b or BKBeta4.
Application
Application
Western blot analysis of BKBeta3a in rat brain membrane lysates using a 1:1000 dilution of
Application Notes
We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).
Additional Information
Form
Liquid
Storage Instructions
Aliquot and store at -20 C. Avoid repeated freeze-thaw cycles.